I am struggling through the same problem, trying to get this PC iPendant software to work from a HMI using windows 10.
If I connect from my laptop, I can get to the iPendant via. my IE. But for some stinking reason, the HMI version of IE does not get past the "Logging in to Controller Please stand by...."
I am at my wits end, disabling the firewall, playing with internet options, adding the ip address to secure sites, and enabling active X to automatically start in settings.
If you ever got past this, and found out what is stopping the Pop-Up window from starting this Active X please let me know.